Guybrush gets in deep (literally!) as his quest for the voodoo exfoliating La Esponja Grande takes a scenic twist -- through the guts of a giant manatee! Trapped in the belly of the beast, our hero encounters a surprising band of castaways, including the long-lost (and obsessive-compulsive) explorer Coronado De Cava. Will sexy pirate hunter Morgan LeFlay prove to be a ruthless enemy, or an unlikely ally? Will the group find La Esponja Grande in time to save Elaine from the rampant Pox of LeChuck?